If you have persistent trouble getting or keeping an erection, you might have erectile dysfunction. These small differences affect the way each medication works, such as how quickly it takes effect and wears off, and the possible side effects. Communicate openly and honestly about your condition. Yes, it can change how you have sex, but those changes aren’t always permanent. Is my erectile dysfunction most likely temporary or chronic?Erectile dysfunction is defined as the persistent inability to achieve or maintain penile erection sufficient for satisfactory sexual performance. The Massachusetts Male Aging . Physical exam. This might include careful examination of your penis and testicles and checking your nerves for sensation. Blood tests. A sample of your blood might be sent to . WHAT IS ERECTILE DYSFUNCTION (ED)? ED affects as many as 30 million men. Most men have problems with erections from time to time. In some men, these problems are .