Insurance: If you plan to use insurance, make sure the online provider accepts it. All PDE5 inhibitors, including Viagra and Cialis, require a valid prescription regardless of the pharmacy or provider. Shipping: Discreet, fast shipping is a must. Brand-name versions of the drug approved for PAH include Adcirca. People with heart conditions should never take ED medications without consulting a doctor. Do I need a prescription for Tadalafil? Though this growth is not cancerous, prostate cancer and BPH can co-occur.Price FAQs Brand-name vs. generic Reducing long-term drug costs Financial assistance Next steps Overview of Cialis Cialis (tadalafil) is a brand-name prescription medication. The Food and Drug. How Cialis Works. Tadalafil and other PDE5 inhibitors primarily work by inducing muscle relaxation. Tadalafil stops the breakdown of a chemical responsible for relaxing muscles. In ED and PAH, the drug targets muscle cells in blood vessels. When the blood vessel muscle cells relax, this expands the vessel and increases blood flow; this . $ (save %) local_offer_outlined Avg retail price $ medication_outlined Availability Available See GoodRx coupons warning Are you looking for information on Adcirca (tadalafil) instead? What is Tadalafil (Cialis)? Drug Facts Common Brands Cialis Drug Class PDE-5 inhibitor.