You may attempt sexual activity at any time between doses. Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medicine. Tadalafil was approved in in the United States for the treatment of pulmonary arterial hypertension [28] and is under regulatory review in other regions for this condition. It may take some time and trial and error to determine the best dosage as well as the best time to take Cialis. If you experience chest pain, dizziness, or nausea during sexual activity, call your doctor immediately or get emergency medical treatment, and avoid sexual activity until your doctor tells you otherwise. Other uses for this medicine This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.The average cost for 30 Tablet(s), 5mg each of the generic (tadalafil) is $ You can buy tadalafil at the discounted price of $ by using the MDRx coupon, a savings of 93%. Even if this drug is covered by Medicare or your insurance, we recommend you compare prices. As needed for ED: 5 to 20 mg by mouth as a one-time dose, with a maximum of one dose in 24 hours. Effects may last up to 36 hours. Daily dosing for ED: or 5 mg by mouth daily. For daily dosing, the maximum dose is 5 mg per day. The medication should be taken once daily at about the same time every day to maintain a consistent level of. The cost for tadalafil oral tablet 5 mg is around $27 for a supply of 90 tablets, depending on the pharmacy you visit. Quoted prices are for cash-paying customers and are not valid .