Severe liver disease. The generic versions are just as effective and much less expensive. Avanafil Stendra. Here are some key factors to consider when deciding: Pricing: Know how much your monthly supply will cost with shipping and tax. These PDE5 inhibitors may cause headache, flushing, drop in blood pressure, or other adverse effects. It lasts 4 to 5 hours, or longer if you have mild to moderate ED.Common Brands Viagra Drug Class PDE-5 inhibitor Controlled Substance Classification Not a controlled medication Generic Status Lower-cost generic available . Sildenafil (Viagra). Tadalafil (Cialis). Vardenafil. These medicines are called PDE5 inhibitors. They enhance the effects of a chemical the body makes that relaxes . Erectile dysfunction can be challenging to discuss, but online treatment offers a private, stress-free solution. Sesame offers simplistic virtual consultations and generic ED medications, Viagra and Cialis, shipped directly to See more.